PK-PD Modeling & Simulation > Asan Preclinical Evaluation center for cancer therapeutiX

Identification of drug characteristics and future prediction through PK-PD modeling

  • Characterization and prediction of drug properties using PK-PD modeling
  • Prediction of human PK-PD based on cell and animal study results using modeling and simulation
  • Understanding drug properties through PK-PD modeling from the discovery or preclinical stages to inform development strategies
  • Designing early-phase clinical trials, such as first-in-human (FIH) studies

Service

  • Consulting on pharmacokinetic-pharmacodynamic (PK-PD) data analysis and development strategy formulation in preclinical and clinical stages.
  • Preparation of PK-PD data analysis reports.
  • Population PK-PD modeling analysis using NONMEM.
  • Physiologically Based Pharmacokinetic (PBPK) modeling based on systems pharmacology and physiology.
  • Development strategy formulation through clinical trial simulations.
  • IVIVC(In vitro, in vivo Correlation).
  • First-in-human clinical trial design.
  • Development of user-friendly tools for applying modeling results in practice.
  • Preparation of result reports based on reproducible research.

PK-PD Simulation